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Week 6 [19-25.11.18] Gene Editing

Science advances at breakneck speed these days. We read reports about new inventions and technologies almost daily. And people sometimes stop and ask: are we sure we should invent it? Isn’t it dangerous to ourselves?
Not so long there was a lot of discussion about AI. How we should proceed cautiously, or we might lose control over it and maybe even risk our own existence by inventing one. But Computer Science is not the only field with such dangerous ideas.
John Oliver decided to summarize, in his own unique way, what we now know about Gene Editing. We have a technology available which allows us to rewrite genes of a living organism. We can even create new genes which can be passed from parents to their child. But isn’t it a bit dangerous? Is it without any risk?
I hope you'll enjoy his presentation :)




Questions:
1.    Did you know how advanced are we in the field of Gene Editing?
2.    Do you think it can be used for the good of the human race?
3.    What dangers do you see in its use?

Comments

I see nothing bad in gene editing. Except one thing. Imagine one thing: you have a button, which, when pressed, makes you feel pleasure. You certain that it does not affect your health in any way. Your brain just feels constant happiness. How do you think, would you press it? And if you would, what could make you stop pressing it? See, the brain is blocked. It feels constant pleasure, and its only concern now is to give the body orders to press that button. Such experiment was already taken on mice. As you might guess -- results are terrifying. All mice just simply died of hunger, constantly pressing that button.

The main problem with the gene editing would be the same: people do not know, when to stop. Our perception is limited with our senses that nature gave us. If we modify them, the outcome will not be that easy to predict. And, of course, we will aim for making everyone happy, effectively dooming us.
Lukasz Mroczek said…
Yes, I knew how advanced we are in gene editing because my fiancée is making such things and I’m always interested and I ask her about it. She is making her own experiments to find a way to cure children’s leukemia and she is making different things with genes.
I think that for sure it can be used for the good of the human race because I see my fiancée working on it but also there are some disadvantages. Some people may have bad intentions and use gene editing in bad ways, only for their purposes.
I don't really think our aim is to make everyone happy no matter the costs. If it was so, we all would end up with an electrode stimulating our pleasure centers a long time ago :)

I think the main problem with gene editing is: we can't really predict all the consequences of even small changes. Like in this example with a mice - we might end up killing some other animals down the food chain if we are not careful.
Iman Masjedi said…
I am familiar with the genetic manipulation and genetic modification partly because I am a close friend of genetic specialist.

We can use genetic modification to help human beings, one of the ways that can come to human help is the numerous treatment of congenital defects, which can be completely eradicated by genetic modification.
but one of the disadvantage of Gene Editing is : This system, if needs to be used for patient therapies and cells need to be reintroduced into the patients, requires cells to be actively dividing ( the only way to have enough edited cells to heal the patient). what happens is that as consequence of the editing or the manufacturing that occurs before and after the editing, cells my stop dividing or dividing at very low rate. So that the number will be insufficient to out compete the malignant cells.
John Oliver is very funny man, always found some jokes. I read articles where was explained what it is and how it works. Also, how USA and China used CRISPR technology to alter DNA of human embryos, but they had one of the strict conditions of the experiment, they must destruction of the embryos after two days. It could help to treat diseases, but also it could be too dangerous, because who knows what will be in future with person who had edited gene. To find out how it affects a person, scientific need to experiment on people, but it's illegal and here we have problem which is unlikely to find a legal solution.
1. I have no idea how advanced we are in this field of science :(

2. I think that if it is intelligently used, it makes sense.

3.If it hits unauthorized hands, this threat is always there. In total, the mother of nature does not like how we interferes
in her area
s18716 said…
Of course, this scientific field can be used for the benefit of mankind. Just like now, with the help of genetic modifications, the best properties of products in various industries are selected. Even if we take the food industry, now such modifications are very actively used in this area, but of course, I do not exclude the fact that it is always beneficial for the consumer.
Very high risk of using these technologies in human genes. It seems to me very dangerous, and it can have unpleasant consequences.
I’m definitely all for unicorns and beefy beagles, as well as ridding the Earth of mosquitos. On a more serious note, I’m always happy to hear of new inventions and developments, especially in the medical field. There’s a great potential in gene editing and its possible applications, and it makes me hopeful for the future. But at the same time the problems that were brought on will need to be addressed before we can benefit from any of it. Frankly, I’m not sure if I’m more afraid of widespread application of eugenics, or bumping into a furry person on the street. Designer babies are one thing, but what about sportsmen designed for performance – essentially a genetic doping. What about super soldiers. Or an actual morality hell – developing biological robots in our image. Will that be slavery and abuse, playing god, or just a clever application of science to further our goals? I have high hopes for gene editing and the good it can do for us, but I recognize that humanity still has to mature before it can be allowed to wield this sort of power over itself.
ExoKuzo said…
I heard news here and there about how far we have come never really have gotten to explore the field much.

Naturally adancements in that field can be very beneficial if we gain ability to modify our genes to remove for example some genetically passed diseases then why not ?

As with everything that touches genes long term evaluations are almost impossible, that not only slows our research but also makes us more hesitant in going forward. We have to keep in mind that its dangerous from social and political perspective since no ordinary "human" could go "check" their genes at wish its not simple to do so so any malicious modifications would come without our knowledge.
Marcin Zając said…
1. Did you know how advanced are we in the field of Gene Editing?
Yes I know, becouse I'm interested in this topic. I wrote article about it for the next week.

2. Do you think it can be used for the good of the human race?
Ofcourse, it's great tool to treat a lot of genetic diseases, for which currently there are not other treatments.

3. What dangers do you see in its use?
It enables creation "super soldiers". It also is unethical for me to editing children before born, for example editing color of eyes or increase of IQ. It can looks like children creation.

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